miRNA description for miR-125b-5p
miRNA accession miR-125b-5p
Species Homo sapiens
 miR-125b-5p identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells [Exosomes] 29472616   
Colorectal cancer cells [Exosomes] 29472616   
Colorectal cancer cells [Exosomes] 29472616   
Lung cells [Microvesicles] 20079801   
Mesenchymal stem cells [Exosomes] 33479185   
Mesenchymal stem cells [Extracellular vesicles] 34596354   
Posterior longitudinal ligament [Small extracellular vesicles] 35513391   
Pulmonary artery endothelial cells [Exosomes] 32132543   
Pulmonary artery endothelial cells [Exosomes] 32132543   
Serum [Exosomes] 27883272   
Serum [Exosomes] 27883272   
Urine [Exosomes] 24352158   
 Experiment description of studies that identified miR-125b-5p in exosomes
1
Experiment ID1435
Identified moleculemiRNA
Identification method miR-chip array
PubMed ID 29472616   
OrganismHomo sapiens
Experiment descriptionMutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
AuthorsCooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC.
Journal name Nat Commun
Publication year2018
SampleColorectal cancer cells
Sample nameHCT116
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miR-chip array
EV-TRACK -
2
Experiment ID1436
Identified moleculemiRNA
Identification method miR-chip array
PubMed ID 29472616   
OrganismHomo sapiens
Experiment descriptionMutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
AuthorsCooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC.
Journal name Nat Commun
Publication year2018
SampleColorectal cancer cells
Sample nameHCT116
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miR-chip array
EV-TRACK -
3
Experiment ID1437
Identified moleculemiRNA
Identification method miR-chip array
PubMed ID 29472616   
OrganismHomo sapiens
Experiment descriptionMutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246
AuthorsCooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC.
Journal name Nat Commun
Publication year2018
SampleColorectal cancer cells
Sample nameHCT116
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miR-chip array
EV-TRACK -
4
Experiment ID324
Identified moleculemiRNA
Identification method Microarray or RT-PCR
PubMed ID 20079801   
OrganismMus musculus
Experiment descriptionMicrovesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
AuthorsAliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ
Journal name Exp Hematol
Publication year2010
SampleLung cells
Sample nameLung cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyFACS
RT-PCR
EV-TRACK EV100071: EV-METRIC:14%
5
Experiment ID1526
Identified moleculemiRNA
Identification method Microarray
PubMed ID 33479185   
OrganismHomo sapiens
Experiment descriptionHuman umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke
AuthorsZhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X.
Journal name Aging
Publication year2021
SampleMesenchymal stem cells
Sample namehUMSCs
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Microarray
EV-TRACK -
6
Experiment ID3202
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 34596354   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p
AuthorsLee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG.
Journal name J Extracell Vesicles
Publication year2021
SampleMesenchymal stem cells
Sample nameAdipose tissue-derived stem cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyFlow cytometry
Small RNA sequencing
ddPCR
EV-TRACK -
7
Experiment ID2740
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 35513391   
OrganismHomo sapiens
Experiment descriptionSmall extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
AuthorsXu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W.
Journal name Nat Commun
Publication year2022
SamplePosterior longitudinal ligament
Sample namePosterior longitudinal ligament cells
Molecules identified in the studymiRNA
Methods used in the studyRNA sequencing
qRT-PCR
EV-TRACK -
8
Experiment ID1468
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
9
Experiment ID1469
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
10
Experiment ID1198
Identified moleculemiRNA
Identification method Microarray
PubMed ID 27883272   
OrganismHomo sapiens
Experiment descriptionCirculating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.
AuthorsHubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ.
Journal name Obesity (Silver Spring).
Publication year2017
SampleSerum
Sample nameTwo weeks before bariatric surgery
Molecules identified in the studymiRNA
Metabolites
Methods used in the studyMass spectrometry
EV-TRACK -
11
Experiment ID1199
Identified moleculemiRNA
Identification method Microarray
PubMed ID 27883272   
OrganismHomo sapiens
Experiment descriptionCirculating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.
AuthorsHubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ.
Journal name Obesity (Silver Spring).
Publication year2017
SampleSerum
Sample nameOne year after bariatric surgery
Molecules identified in the studymiRNA
Metabolites
Methods used in the studyMass spectrometry
EV-TRACK -
12
Experiment ID357
Identified moleculemiRNA
Identification method RNA deep sequencing
PubMed ID 24352158   
OrganismHomo sapiens
Experiment descriptionCharacterization and deep sequencing analysis of exosomal miRNA in human urine
AuthorsLesley Cheng, Xin Sun, Bradley M. Coleman, Andrew F. Hill
Journal name Kidney Int
Publication year2014
SampleUrine
Sample nameUrine - Normal
Molecules identified in the studymiRNA
Methods used in the studyRNA deep sequencing
EV-TRACK EV140147: EV-METRIC:44%, 0%, 22%